Taking the Stage, Breakthrough Stories from Women Leaders


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Collecting The Beat Generation

Health chiefs have now recommended that the procedure is offered routinely on the NHS after patients in a trial saw their lung function triple. The improvement meant they were able once again to walk, talk and complete household chores, all of which had been difficult or impossible before surgery. But Mr Gregg, from Egbaston, Birmingham has had the pioneering new treatment. The implant is a one-way valve which stops airflow into the diseased region of a lung, while simultaneously providing an escape route for harmful fluids and gas. The trial also found that fewer patients needed hospital treatment over a year following treatment, according to results published in the American Journal of Respiratory and Critical Care Medicine.


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The pioneering new treatment could help reduce the 30, people a year killed by COPD. Emphysema occurs when lungs become progressively damaged and the air sacs, which absorb oxygen, stop functioning properly. Doctors can offer lung volume reduction surgery — the removal of parts of the lungs — or use implants to close them off. But it is a drastic option: a third of patients spend days in intensive care afterwards, and a small percentage do not survive the procedure. The new Zephyr valves are between four and seven millimetres long and are shaped a little like a shuttlecock.

They comprise a nickel and titanium alloy wire exterior and soft silicone inner tube. A minuscule opening at the end of the wire basket opens and closes intermittently, providing a one-way escape route for troublesome air and fluid in the malfunctioning section of lung.

Breakthrough for thousands of suffering from COPD

Typically patients will be given two or more valves to block off diseased lung sections, and one or both lungs can be treated. The valves are placed via a bronchoscope — a tube with a camera at the end of it — threaded into the lungs via the mouth, so there are no incisions. Colin Gregg, 74, a company director from Edgbaston, Birmingham, smoked 40 cigarettes a day until he started struggling for breath and gave up 12 years ago. It is horrible.


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Doctors at the Royal Brompton diagnosed emphysema and told him about the Zephyr trial. In July , Colin had four valves implanted into one lung during a minute procedure. Want to learn more about MBC?

That everybody survives cancer now. But everybody does not survive cancer. An estimated ,plus women and men in the U. Between 20 and 30 percent of women with early stage breast cancer go on to develop metastatic disease. While treatable, metastatic breast cancer MBC cannot be cured. The five-year survival rate for stage 4 breast cancer is 22 percent; median survival is three years.

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Annually, the disease takes 40, lives. As with primary breast cancer, treatment for stage 4 breast cancer, such as chemotherapy or radiation, can often be harsh and unforgiving. Many also have to educate others about their disease, explaining over and over that no, the scans and blood tests and treatments will never come to end. No, the metastasized breast cancer in their lungs is neither lung cancer nor linked to smoking.

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In fact, a recent survey sponsored by Pfizer Oncology shows just how misunderstood it is. Sixty percent of the 2, people surveyed knew little to nothing about MBC while 72 percent believed advanced breast cancer was curable as long as it was diagnosed early. The MBC Alliance, a consortium of 29 cancer organizations including the biggest names in breast cancer think Avon, Komen, Susan Love , addressed this lack of understanding and support as well as what many patient advocates term the underfunding of MBC research in a recently published landmark report. You attempt to stabilize the disease.

Schoger said she will remain on this therapy until it stops working. But some women have aggressive disease and just blow through their therapies.

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Others, like Teri Pollastro, a year-old stage 4 patient from Seattle, respond surprisingly well. Diagnosed with early stage ductal carcinoma in situ DCIS in , Pollastro underwent a mastectomy but did not receive chemotherapy, radiation or tamoxifen, since her cancer was ER negative.

How can business advance gender equality across the value chain by engaging men as allies?

Pollastro went on Herceptin, a type of immunotherapy for women with HER2-positive metastatic breast cancer, and did six months of chemotherapy.

Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders
Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders
Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders
Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders
Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders
Taking the Stage, Breakthrough Stories from Women Leaders Taking the Stage, Breakthrough Stories from Women Leaders

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